Download Adjuvant Therapies and Markers of Post-Surgical Minimal by J. Lemerle, M. F. Tournade, C. Patte (auth.), Professor PDF

By J. Lemerle, M. F. Tournade, C. Patte (auth.), Professor Gianni Bonadonna, Professor Georges Mathé, Professor Sydney E. Salmon (eds.)

ISBN-10: 3642813348

ISBN-13: 9783642813344

Show description

Read or Download Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II: Adjuvant Therapies of the Various Primary Tumors PDF

Similar nonfiction_11 books

Cardiac Glycosides

Regardless of outdated classic and two hundred years of scientific use, digitalis continues to be an enticing healing agent, to clinicians in addition to to the pharmacologist, the biochemist, and co-workers in different diciplines of theoretic drugs. while a drug, even if, has such a lot of appealing features, it sort of feels right and aJvis­ capable for the luck of a systematic assembly to target a few well-defined elements.

Free Radicals and the Liver

In accordance with the result of the newest congress of the eu organization for the research of the Liver (EASL), this quantity makes very good analyzing because it explores intimately the position of unfastened radical reactions in liver ailments. reviews in recent times utilizing a variety of equipment have proven that unfastened radicals play a massive function in poisonous liver issues.


This exhibition heralds a chain of thematic exhibits conceived to ascertain quite a few components within the historical past of gown, with decisions culled basically from the Museums personal collections. hence reaffirming the Museums dedication to accumulating and to the care and show of dress, those installations will provide titanic monitors 12 months around in addition to a unprecedented chance to judge and relish the evolution of dress over the past 3 centuries.

Plant Viruses

In getting ready the 5th version of Plant Viruses the overall plan of the booklet has been retained on account that this turns out to provide enough scope for a publication of this measurement. although, each one part has been introduced up to date with any new info which has develop into on hand because the e-book of the former version.

Additional resources for Adjuvant Therapies and Markers of Post-Surgical Minimal Residual Disease II: Adjuvant Therapies of the Various Primary Tumors

Sample text

Townsend, C. , Eilber, F. , Morton, D. : Skeletal and soft tissue sarcomas: results of surgical adjuvant chemotherapy. Proc. Am. Soc. Clin. Onc. 17, 265-270 (1976) 20. : Enterale und parenterale Leucovorin-Medikation nach MethotrexatStof3behandlung maligner Tumoren. Med. Klinik 71, 1720-1723 (1976) 21. : Dihydrofolat-Reduktase und Thymidin-Kinase im Knochenmark unter Einwirkung von Foisaureantagonisten. Klin. Wochenschr. 45, 987-994 (1967) 22. : DNS-Synthese in Leukamiezellen unter der Einwirkung von Methotrexat, 5-Fluoro-Uracil und Cytosin-Arabinosid in vitro.

Five others of this group remain disease-free after 21 + to 48+ months. In the second series all four patients remain disease-free after 1+-14+ months. Figure 1 shows the actuarial analysis of diseasefree survival for the total series of 19 patients. The present findings indicate that amputation followed by intermittent treatment with the maximum tolerated doses of ADM has not significantly improved the 2-year relapse rate over that obtained with surgery alone. Only a moderate increase in the disease-free status was achieved, and our results appear definitely inferior to those reported by other authors utilizing ADM as adjuvant therapy [3].

The results of protocol B are better and seem comparable to the results published by CORTES et al. We have not enough patients to determine whether the semicontinuous chemotherapy has had any additional beneficial effects. However, even for protocol B, the overall results are not fully satisfactory, considering that we have a maximum of2 years follow-up and that the risk oflate metastases persists. The tolerance and toxic cost of protocol A is also not negligible and was ascribed mainly to the use of high-dose methotrexate.

Download PDF sample

Rated 4.65 of 5 – based on 31 votes